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In the study, normal mice with a muscle injury received steroids just before injury and for two weeks after the injury. The injections of testosterone caused the mice to develop muscle loss in six to eight weeks but the steroid did not cause muscle atrophy in other tissues of mice.
In addition, the researchers found that injection of testosterone for three months significantly increased the rate of muscle recovery in mice with damaged muscle that had already gone through a muscle atrophy phase.
"This study provides substantial new information on how testosterone can be used to induce muscle regeneration in a tissue with known muscle injury, using an in vivo model of muscle atrophy," said Thomas L, clenbuterol before and after male. Hickey, M, clenbuterol before and after male.D, clenbuterol before and after male., professor of medicine and co-senior author of the study, clenbuterol before and after male.
Hickey said testosterone is an effective drug in the treatment of male pattern baldness and other male sexual dysfunction.
"We have known for a long time that there are benefits of increasing testosterone levels in male pattern baldness, but this experiment shows how this hormone can have an important impact on muscle recovery," he said, clenbuterol before and after 3 weeks.
Hickey presented the results of this experimental study on September 25 as part of the annual meeting of the Endocrine Society Annual Meeting in Atlanta, and 3 before weeks after clenbuterol.
This research was supported by the National Institutes of Health (RO1-CA-041848, RO1-CA-102972), Stony Brook University (RO1-CA-111909, RO1-CA-095824), Harvard Medical School (MRS-08-HL076832), Wyeth, Incorporated and the National Center for Advancing Translational Sciences (TCAST) at Stanford University.
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